Ambient Aqueous Synthesis of Ultrasmall PEGylated Cu_2−xSe Nanoparticles as a Multifunctional Theranostic Agent for Multimodal Imaging Guided Photothermal Therapy of Cancer

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• 作者：Shaohua Zhang ; Caixia Sun ; Jianfeng Zeng ; Qiao Sun ; Guanglin Wang ; Yong Wang ; Yan Wu ; Shixue Dou ; Mingyuan Gao and Zhen Li
• 刊名：Advanced Materials
• 出版年：2016
• 出版时间：October 26, 2016
• 年：2016
• 卷：28
• 期：40
• 页码：8927-8936
• 全文大小：3136K
• ISSN：1521-4095

文摘

Ultrasmall PEGylated Cu_2–xSe nanoparticles with strong near-infrared absorption have been prepared by an ambient aqueous method. The resultant water-soluble and biocompatible nanoparticles are demonstrated to be a novel nanotheranostic agent for effective deep-tissue photoacoustic imaging, computed tomography imaging, single-photon emission computed tomography imaging, and photothermal therapy of cancer.