ChemInform Abstract: Fei-Phos Ligand-Controlled Asymmetric Palladium-Catalyzed Allylic Substitutions with Structurally Diverse Nucleophiles: Scope and Limitations.
The allylic etherification of alcohols and the allylic alkylation of activated methylene compounds, indoles, and aromatic amines proceed with good yields and high enantioselectivity (up to 99% e.e.) employing Fei-Phos as an effective phosphine ligand.