A Multifunctional Biomaterial with NIR Long Persistent Phosphorescence, Photothermal Response and Magnetism

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• 作者：Yiling Wu ; Dr. Yang Li ; Xixi Qin and Prof. Dr. Jianrong Qiu
• 刊名：Chemistry – An Asian Journal
• 出版年：2016
• 出版时间：September 20, 2016
• 年：2016
• 卷：11
• 期：18
• 页码：2537-2541
• 全文大小：1218K
• ISSN：1861-471X

文摘

There are many reports on long persistent phosphors (LPPs) applied in bioimaging. However, there are few reports on LPPs applied in photothermal therapy (PTT), and an integrated system with multiple functions of diagnosis and therapy. In this work, we fabricate effective multifunctional phosphors Zn₃Ga₂SnO₈: Cr³⁺, Nd³⁺, Gd³⁺ with NIR persistent phosphorescence, photothermal response and magnetism. Such featured materials can act as NIR optical biolabels and magnetic resonance imaging (MRI) contrast agents for tracking the early cancer cells, but also as photothermal therapeutic agent for killing the cancer cells. This new multifunctional biomaterial is expected to open a new possibility of setting up an advanced imaging-guided therapy system featuring a high resolution for bioimaging and low side effects for the photothermal ablation of tumors.