Facile Synthesis of Polysubstituted Imidazoles through CBr₄-Mediated Tandem Cyclization of Amidines with 1,3-Dicarbonyl Compounds or Ketones

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• 作者：Xiaoqiang Zhou ; Haojie Ma ; Chong Shi ; Yixin Zhang ; XingXing Liu and Guosheng Huang
• 刊名：European Journal of Organic Chemistry
• 出版年：2017
• 出版时间：January 10, 2017
• 年：2017
• 卷：2017
• 期：2
• 页码：237-240
• 全文大小：660K
• ISSN：1099-0690

文摘

Polysubstituted imidazoles were synthesized in a facile metal-free CBr₄-mediated tandem cyclization of amidine with 1,3-dicarbonyl compounds or ketones. The desired products were obtained in moderate to good yields by using simple operation techniques and mild conditions.