Photothermal Therapy: Light-Triggered Assembly of Gold Nanoparticles for Photothermal Therapy and Photoacoustic Imaging of Tumors In Vivo (Adv. Mater. 6/2017)

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• 作者：Xiaju Cheng ; Rui Sun ; Ling Yin ; Zhifang Chai ; Haibin Shi and Mingyuan Gao
• 刊名：Advanced Materials
• 出版年：2017
• 出版时间：February 10, 2017
• 年：2017
• 卷：29
• 期：6
• 全文大小：1514K
• ISSN：1521-4095

文摘

Diazirine-decorated gold nanoparticles (AuNPs), which can form covalently crosslinked aggregates upon laser irradiation (λ = 405 nm) are reported by H. Shi, M. Y. Gao and co-workers in article 1604894. Both in vitro and in vivo studies indicate that light-triggered assembly remarkably shifts the surface plasmon resonance of the Au particles to near-infrared regions, which, in consequence, effectively enhances the efficacy of photothermal therapy and sensitivity of photoacoustic imaging of tumours.