Light-Triggered Assembly of Gold Nanoparticles for Photothermal Therapy and Photoacoustic Imaging of Tumors In Vivo

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• 作者：Xiaju Cheng ; Rui Sun ; Ling Yin ; Zhifang Chai ; Haibin Shi and Mingyuan Gao
• 刊名：Advanced Materials
• 出版年：2017
• 出版时间：February 10, 2017
• 年：2017
• 卷：29
• 期：6
• 全文大小：2512K
• ISSN：1521-4095

文摘

Photocross-linkable Au nanoparticles are prepared through surface decoration of photolabile diazirine moieties. Both in vitro and in vivo studies indicate that the light-triggered cross-linking can dramatically shift the surface plasmon resonance of Au nanoparticles to near-infrared regions, which in consequence remarkably enhances their efficacy for photothermal therapy and photoacoustic imaging of tumors in vivo.