Fluorogenic 2D Peptidosheet Unravels CD47 as a Potential Biomarker for Profiling Hepatocellular Carcinoma and Cholangiocarcinoma Tissues

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• 作者：Yun-Han Ma ; Wei-Tao Dou ; Yu-Fei Pan ; Li-Wei Dong ; Ye-Xiong Tan ; Xiao-Peng He ; He Tian and Hong-Yang Wang
• 刊名：Advanced Materials
• 出版年：2017
• 出版时间：February 2, 2017
• 年：2017
• 卷：29
• 期：5
• 全文大小：2133K
• ISSN：1521-4095

文摘

A 2D peptidosheet unravels CD47 as a potential biomarker to image hepatocarcinoma and cholangiocarcinoma cells and tissues. Supramolecular assembly between water-soluble 2D MoS₂ and a peptide probe produces the 2D peptidosheet suited for the profiling of hepatocarcinoma and cholangiocarcinoma tissues over healthy tissues on clinical specimens.