Endoplasmic reticulum stress is involved in apoptosis of detrusor muscle in streptozocin-induced diabetic rats

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• 作者：Dongwen Wang ; Xiaobin Yuan ; Caoyang Hu ; Bin Zhang ; Hongfei Gao ; Dong Wang ; Junjie Chi ; Qiang Jing ; Shulin Wu and Chin-Lee Wu
• 刊名：Neurourology and Urodynamics
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：36
• 期：1
• 页码：65-72
• 全文大小：1762K
• ISSN：1520-6777

文摘

Endoplasmic reticulum stress (ERS) has been proven to be associated with apoptosis and plays a critical role in the development of many diabetic complications. In the pathogenesis of diabetic cystopathy (DCP), the role of ERS is still unclear. Our study is aimed at the investigation of the involvement of ERS-associated detrusor muscle apoptosis in streptozocin (STZ)-induced diabetic rats.