Agarose bioplastic-based drug delivery system for surgical and wound dressings

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• 作者：Ankur Awadhiya ; Suhela Tyeb ; Kalpana Rathore and Vivek Verma
• 刊名：Engineering in Life Sciences
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：17
• 期：2
• 页码：204-214
• 全文大小：1859K
• ISSN：1618-2863

文摘

We have developed an agarose-based biocompatible drug delivery vehicle. The vehicle is in the form of thin, transparent, strong and flexible films. The biocompatibility and haemocompatibility of the films is confirmed using direct and indirect contact biological assay. Contact angle measurement exhibits hydrophilic nature of the films, and protein adsorption test shows low protein adsorption on the film surface. Drugs, antibiotics and antiseptics, retain their potency after their incorporation into the films. Our bioplastic films can be a versatile medium for drug delivery applications, especially as wound and surgical dressings where a fast drug release rate is desired.