Detection of phenazepam in illicitly manufactured Erimin 5 tablets

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• 作者：Wendy J.L. Lim ; Angeline T.W. Yap ; Merula Mangudi ; H.B. Koh ; Angeline S.Y. Tang and K.B. Chan
• 刊名：Drug Testing and Analysis
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：9
• 期：2
• 页码：293-305
• 全文大小：1286K
• ISSN：1942-7611

文摘

A validated ultra-high-performance liquid chromatographic (UHPLC) method was used to determine the phenazepam dosage in clandestinely produced Erimin 5 tablets. Tablets from five different seizures submitted to the laboratory in 2013 were found to have a dosage of about 2.4 milligrams. The measurement uncertainty of the assay was estimated to be 3.2 % (relative) at a coverage factor of k=2. As an adjunct study the dyes in the tablets from several seizures were determined by thin-layer chromatography (TLC) for future comparative studies.