Preparation and properties of reversible hydrogels based on triblock poly(amino acid)s with tunable pH-responsivity across a broad range

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• 作者：Dedai Lu ; Yongyong Zhang ; Yunfei Li ; Chen Luo ; Xiangya Wang ; Xiaolin Guan ; Hengchang Ma ; Xiaolong Zhao ; Qiangbing Wei and Ziqiang Lei
• 刊名：Journal of Polymer Science Part A: Polymer Chemistry
• 出版年：2017
• 出版时间：January 15, 2017
• 年：2017
• 卷：55
• 期：2
• 页码：207-212
• 全文大小：574K
• ISSN：1099-0518

文摘

A series of reversible triblock poly(amino acid)s hydrogels with tunable pH-responsivity (pH 3.5–10.0) were synthesized by adjusting the ratio of the blocks. Attributing to the good biodegradability and low cytotoxicity of these triblock poly(amino acid)s, it is obvious that these poly(amino acid)s are potential novel materials in drug delivery and injectable hydrogels.