Mass Cytometry Analytical Approaches Reveal Cytokine-Induced Changes in Natural Killer Cells

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• 作者：Elena Vendrame ; Julia Fukuyama ; Dara M. Strauss-Albee ; Susan Holmes and Catherine A. Blish
• 刊名：Cytometry Part B: Clinical Cytometry
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：92
• 期：1
• 页码：57-67
• 全文大小：1118K
• ISSN：1552-4957

文摘

Natural killer (NK) cells have antiviral and antitumor activity that could be harnessed for the treatment of infections and malignancies. To maintain cell viability and enhance antiviral and antitumor effects, NK cells are frequently treated with cytokines. Here they performed an extensive assessment of the effects of cytokines on the phenotype and function of human NK cells.