Evidence of a dual histogenetic pathway of sacrococcygeal teratomas

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• 作者：Robert E Emerson ; Chia-Sui Kao ; John N Eble ; David J Grignon ; Mingsheng Wang ; Shaobo Zhang ; Xiaoyan Wang ; Rong Fan ; Timothy A Masterson ; Lawrence M Roth and Liang Cheng
• 刊名：Histopathology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：70
• 期：2
• 页码：290-300
• 全文大小：1195K
• ISSN：1365-2559

文摘

Sacrococcygeal teratomas are rare tumours that occur most frequently in neonates, although adult cases also occur. The molecular pathogenesis of these tumours and their long-term prognosis is uncertain. We investigated the i(12p) status of a large number of primary sacrococcygeal teratomas in both children and adults, including cases with malignant germ cell tumour elements.