The Relationship between the Methylated Septin-9 DNA Blood Test and Stool Occult Blood Test for Diagnosing Colorectal Cancer in Taiwanese People

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• 作者：Chung-Hung Chen ; Sheng-Lei Yan ; Tsung-Hsun Yang ; Shih-Feng Chen ; Yung-Hsiang Yeh ; Jing-Jim Ou ; Chien-Hua Lin ; Yueh-Tsung Lee and Chien-Hua Chen
• 刊名：Journal of Clinical Laboratory Analysis
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：31
• 期：1
• 全文大小：161K
• ISSN：1098-2825

文摘

Colorectal cancer (CRC) is a common and lethal disease in the world. There is an increasing number of cases in Taiwan and a higher rate at advanced stages. The immune fecal occult blood test (iFOBT) has been used as a screening method in Taiwan for years. A new novel diagnostic tool, the Methylated Septin-9 (MS-9) DNA blood test, had been reported to have high sensitivity and specificity for CRC detection. There are no available data in Taiwan, so we conducted this prospective randomized trial to investigate the relationship among the MS-9 DNA blood test, iFOBT, and a combination of the two tests for diagnosing CRC in Taiwanese people.