Novel Organotellurium Heterocycles Derived From Bis(2-Aminophenyl) Ditelluride

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• 作者：Gabrielle Sanford ; Kaitlynn E. Walker ; Frank R. Fronczek and Thomas Junk
• 刊名：Journal of Heterocyclic Chemistry
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：54
• 期：1
• 页码：575-579
• 全文大小：254K
• ISSN：1943-5193

文摘

Novel methods for the preparation of organotellurium heterocycles derived from bis(2-aminophenyl) ditelluride were developed. Thus, highly nucleophilic 2-aminobenzenetellurol generated by reduction in situ reacted smoothly with malonitrile to 2-cyanomethylbenzo-1,3-tellurazole, while its treatment with carbon disulfide and subsequent methylation generated 2-methylmercaptobenzo-1,3-tellurazole. Amidation to (2-haloacetamidophenyl) ditellurides, followed by reduction under carefully controlled conditions, furnished previously inaccessible 2H-1,4-benzotellurazin-3(4H)-ones in yields ranging from 47-62%.