Integration of expression quantitative trait loci and pleiotropy identifies a novel psoriasis susceptibility gene, PTPN1

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• 作者：Xianyong Yin ; Yuan Lin ; Changbing Shen ; Ling Wang ; Xianbo Zuo ; Xiaodong Zheng ; Sen Yang ; Jianjun Liu ; Kirk C. Wilhelmsen and Xuejun Zhang
• 刊名：The Journal of Gene Medicine
• 出版年：2017
• 出版时间：January-February 2017
• 年：2017
• 卷：19
• 期：1-2
• 全文大小：180K
• ISSN：1521-2254

文摘

Psoriasis is a common inflammatory skin disease, whereas schizophrenia is a psychiatric disorder with substantial comorbidity. Although these two disorders manifest with apparently unrelated phenotypes, there is some evidence suggesting that they share common genetic factors.