Glomeruli or interstitium targeted by inter-renal injections supplemented by electroporation: Still a useful tool in renal research

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• 作者：Xing Mao ; Fang Li ; Nianji Yang ; Chenyang Qi ; Steven Qian Zhang ; Zhigang Zhang and Huijuan Wu
• 刊名：The Journal of Gene Medicine
• 出版年：2016
• 出版时间：November-December 2016
• 年：2016
• 卷：18
• 期：11-12
• 页码：343-352
• 全文大小：2018K
• ISSN：1521-2254

文摘

Studies concerning proteins are always a crucial part of renal research. As a result of current technologies, scientists have mastered several techniques for generating genetically modified animals. However, in most cases, accessing these animals is still time-consuming and often expensive. This makes the alteration of protein expression by in vivo plasmid transfection an easily-accessible alternative. However, there is still no comprehensive study describing where plasmids would be expressed when they are injected into the kidneys.