Cobalt-Catalyzed Mild Ring-Opening Addition of Arenes C−H Bond to 7-Oxabicyclic Alkenes

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• 作者：Krishnamoorthy Muralirajan ; Sekar Prakash and Chien-Hong Cheng
• 刊名：Advanced Synthesis & Catalysis
• 出版年：2017
• 出版时间：February 2, 2017
• 年：2017
• 卷：359
• 期：3
• 页码：513-518
• 全文大小：2510K
• ISSN：1615-4169

文摘

A mild approach for a Cp*Co(III)-catalyzed C−H naphthylation of arenes by 7-oxabicyclic alkenes has been developed. In some cases, intermediate products with a 1,2-dihydronaphthalen-1-ol group have been isolated at room temperature in good yield. The catalytic reaction proceeds via C−H activation, insertion, β-oxygen elimination, protonation, and dehydration, respectively. These simple protocols, featuring mild conditions and tolerance of functional groups, exhibit great potential for a variety of synthetic applications.