Cover Picture: Atmosphere- and Temperature-Controlled Regioselective Aminobromination of Olefins (Adv. Synth. Catal. 2/2017)

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• 作者：Wesley Zongrong Yu ; Yi An Cheng ; Ming Wah Wong and Ying-Yeung Yeung
• 刊名：Advanced Synthesis & Catalysis
• 出版年：2017
• 出版时间：January 19, 2017
• 年：2017
• 卷：359
• 期：2
• 页码：178
• 全文大小：3247K
• ISSN：1615-4169

文摘

The inside cover picture, provided by Wesley Zongrong Yu, Yi An Cheng, Ming Wah Wong and Ying-Yeung Yeung, illustrates the reversal of regioselectivity in the aminobromination of alkenes by small changes in the temperature and reaction atmosphere. The Markovnikov product β-bromoamide was formed at 25 °C without the use of an inert atmosphere. In sharp contrast, the reversal of regioselectivity to form the opposite regioisomer the α-bromoamide occurred at 40 °C under an argon atmosphere, through a switch in mechanistic pathway. Details can be found in the communication on pages 234–239 (W. Z. Yu, Y. A. Cheng, M. W. Wong, Y.-Y. Yeung, Adv. Synth. Catal. 2017, 359, 234–239; DOI: 10.1002/adsc.201600821).