Facile Fabrication of Dendritic Mesoporous SiO2@CdTe@SiO2 Fluorescent Nanoparticles for Bioimaging

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• 作者：Shaohua Zhang ; Ling Wen ; Jianping Yang ; Jianfeng Zeng ; Qiao Sun ; Zhen Li ; Dongyuan Zhao and Shixue Dou
• 刊名：Particle & Particle Systems Characterization
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：33
• 期：5
• 页码：261-270
• 全文大小：6178K
• ISSN：1521-4117

文摘

A seeded watermelon-like mesoporous nanostructure (mSiO₂@CdTe@SiO₂, mSQS) composed of a novel dendritic mesoporous silica core, fluorescent CdTe quantum dots (QDs), and a protective solid silica shell is successfully fabricated by loading QDs into dendritic mesoporous silica nanoparticles through electrostatic interaction, and then coating with a solid silica shell by the modified Stöber method. The shell thickness of mSQS can be tuned from 0 to 32 nm as desired by controlling the reaction parameters, including the amount of silica precursor, tetraethyl orthosilicate, that is introduced, the solvent ratio (H₂O:ethanol), and the amount of catalyst (NH₃⋅H₂O). These fluorescent mSiO₂@QDs@SiO₂ nanoparticles possess excellent stability and thickness-dependent cytotoxicity, and are successfully applied to bioimaging.