Metal-Free Cross-Coupling of Arylboronic Acids and Derivatives with DAST-Type Reagents for Direct Access to Diverse Aromatic Sulfinamides and Sulfonamides

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• 作者：Qiang Wang ; Prof. Dr. Xiang-Ying Tang and Prof. Dr. Min Shi
• 刊名：Angewandte Chemie
• 出版年：2016
• 出版时间：August 26, 2016
• 年：2016
• 卷：128
• 期：36
• 页码：10969-10973
• 全文大小：672K
• ISSN：1521-3757

文摘

We have developed a simple and convenient method for the cross-coupling of arylboronic acids and their derivatives with DAST-type reagents under mild and metal-free conditions to directly afford sulfinamides in moderate to good yields. Moreover, sulfonamides were obtained after a simple oxidation reaction. The reaction mechanism was investigated by ¹⁸O-labeling experiments, and the synthetic utility was demonstrated by the sulfoxidation of natural products.