Rhodium-Catalyzed Intramolecular C−H Silylation by Silacyclobutanes

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• 作者：Dr. Qing-Wei Zhang ; Kun An ; Li-Chuan Liu ; Shuangxi Guo ; Chenran Jiang ; Dr. Huifang Guo and Prof. Dr. Wei He
• 刊名：Angewandte Chemie
• 出版年：2016
• 出版时间：May 17, 2016
• 年：2016
• 卷：128
• 期：21
• 页码：6427-6431
• 全文大小：624K
• ISSN：1521-3757

文摘

Silacyclobutane was discovered to be an efficient C−H bond silylation reagent. Under the catalysis of Rh^I/TMS-segphos, silacyclobutane undergoes sequential C−Si/C−H bond activations, affording a series of π-conjugated siloles in high yields and regioselectivities. The catalytic cycle was proposed to involve a rarely documented endocyclic β-hydride elimination of five-membered metallacycles, which after reductive elimination gave rise to a Si−Rh^I species that is capable of C−H activation.