ChemInform Abstract: Tandem gem-Dichlorination and Nitrile Oxide Generation from Chlorochromene Aldoximes: Synthesis of a New Class of Room Temperature Fluxional 4-Chromanone Derivatives.
N-Chlorosuccinimide is used for the geminal dichlorination which proceeds in a tandem one-pot approach together with a cyclization with terminal alkynes or alkenes to give dichlorochromanone isoxazole and isoxazoline derivatives.