Intrinsically Zirconium-89 Labeled Gd2O2S:Eu Nanoprobes for In Vivo Positron Emission Tomography and Gamma-Ray-Induced Radioluminescence Imaging

详细信息    查看全文

• 作者：Yonghua Zhan ; Fanrong Ai ; Feng Chen ; Hector F. Valdovinos ; Hakan Orbay ; Haiyan Sun ; Jimin Liang ; Todd E. Barnhart ; Jie Tian and Weibo Cai
• 刊名：Small
• 出版年：2016
• 出版时间：June 1, 2016
• 年：2016
• 卷：12
• 期：21
• 页码：2872-2876
• 全文大小：7473K
• ISSN：1613-6829

文摘

The engineering of a novel dual-modality imaging probe is reported here by intrinsically labeling zirconium-89 (⁸⁹Zr, a positron emission radioisotope with a half-life of 78.4 h) to PEGylated Gd₂O₂S:Eu nanophorphors, forming [⁸⁹Zr]Gd₂O₂S:Eu@PEG for in vivo positron emission tomography/radioluminescence lymph node mapping.