DBU-Mediated [3+2] Cycloaddition Reactions of Donor-Acceptor Cyclopropanes with Nitromethane: Efficient Strategy for the Construction of Isoxazole Skeletons

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• 作者：Shuwen Xue ; Jiaming Liu and Cunde Wang
• 刊名：European Journal of Organic Chemistry
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：2016
• 期：14
• 页码：2450-2456
• 全文大小：954K
• ISSN：1099-0690

文摘

A new DBU-mediated [3+2] cycloaddition reaction has been developed using readily available donor–acceptor cyclopropanes and nitromethane. This approach provides a straightforward and efficient route to the construction of polysubstituted isoxazole scaffolds in high yields.