Association of homocysteine level and vascular burden and cognitive function in middle-aged and older adults with chronic kidney disease

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• 作者：Yi-Chun Yeh ; Mei-Feng Huang ; Shang-Jyh Hwang ; Jer-Chia Tsai ; Tai-Ling Liu ; Shih-Ming Hsiao ; Yi-Hsin Yang ; Mei-Chuan Kuo and Cheng-Sheng Chen
• 刊名：International Journal of Geriatric Psychiatry
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：31
• 期：7
• 页码：723-730
• 全文大小：127K
• ISSN：1099-1166

文摘

Patients with chronic kidney disease (CKD) have been found to have cognitive impairment. However, the core features and clinical correlates of cognitive impairment are still unclear. Elevated homocysteine levels are present in CKD, and this is a risk factor for cognitive impairment and vascular diseases in the general population. Thus, this study investigated the core domains of cognitive impairment and investigated the associations of homocysteine level and vascular burden with cognitive function in patients with CKD.