Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds

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• 作者：Salwa Suliman ; Himalaya Parajuli ; Yang Sun ; Anne Christine Johannessen ; Anna Finne-Wistrand ; Emmet McCormack ; Kamal Mustafa and Daniela Elena Costea
• 关键词：cancer ; microenvironment ; bioluminescence ; tissue engineering ; scaffold
• 刊名：Head & Neck
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：38
• 期：S1
• 页码：E1177-E1187
• 全文大小：22795K
• ISSN：1097-0347

文摘

Microenvironmental cues play a major role in head and neck cancer. Biodegradable scaffolds used for bone regeneration might also act as stimulative cues for head and neck cancer. The purpose of this study was to establish an experimental model for precise and noninvasive evaluation of tumorigenic potential of microenvironmental cues in head and neck cancer.