Significance of mammalian target of rapamycin in patients with locally advanced stage IV head and neck squamous cell carcinoma receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil

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• 作者：Shau-Hsuan Li ; Wei-Che Lin ; Tai-Lin Huang ; Chang-Han Chen ; Tai-Jan Chiu ; Fu-Min Fang ; Wan-Ting Huang ; Cheng-Ming Hsu ; Sheng-Dean Luo ; Chi-Chih Lai ; Yan-Ye Su ; Hui-Ching Chuang and Chih-Yen Chien
• 关键词：head and neck cancer ; squamous cell carcinoma ; mammalian target of rapamycin (mTOR) ; induction chemotherapy ; docetaxel
• 刊名：Head & Neck
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：38
• 期：S1
• 页码：E844-E852
• 全文大小：2186K
• ISSN：1097-0347

文摘

This study evaluated the significance of mammalian target of rapamycin (mTOR) activation on the prognosis of patients with locally advanced head and neck squamous cell carcinoma (HNSCC) receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil (TPF).