Plasminogen activator inhibitor-1 as regulator of tumor-initiating cell properties in head and neck cancers

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• 作者：Yueh-Chun Lee ; Cheng-Chia Yu ; Chih Lan ; Che-Hsin Lee ; Hsueh-Te Lee ; Yu-Liang Kuo ; Po-Hui Wang and Wen-Wei Chang
• 关键词：plasminogen activator inhibitor-1 (PAI-1) ; tiplaxtinin (PAI-039) ; tumor-initiating cells ; head and neck cancer ; Sox2
• 刊名：Head & Neck
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：38
• 期：S1
• 页码：E895-E904
• 全文大小：7080K
• ISSN：1097-0347

文摘

The existence of tumor-initiating cells (TICs) has been described in head and neck cancers. Plasminogen activator inhibitor-1 (PAI-1) has been demonstrated to act as a prognostic factor in head and neck cancers.