Controlled release of osteopontin and interleukin-10 from modified endovascular coil promote cerebral aneurysm healing
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- 作者：Jingyi Chena ; jyxchen@sina.com" class="auth_mail" title="E-mail the corresponding author ; Lijun Yangb ; Yan Chenb ; Gengshen Zhangb ; Zheneng Fanb
- 关键词：MMP-9 ; matrix metallopeptidase 9 ; PLGA ; poly-DL-lactic glycolic acid ; OPN ; osteopontin
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：360
- 期：Complete
- 页码：13-17
- 全文大小：572 K
文摘
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Modify the endovascular coil to lower the recurrence rate
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Modification with osteopontin, IL-10 or matrix metallopeptidase 9 has been tested.
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Osteopontin and IL-10 coated coils show significant improvement in tissue ingrowth while MMP-9 coated coils failed to.
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