Hypodermin A, a potential agent for prevention of allogeneic acute rejection
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- 作者：Quangang Chena ; Renjin Chena ; Jing Liub ; Honghua Yuanc ; Peng Liuc ; Ankang Hua ; Lianlian Wua ; Liurong Fangd ; e ; Shaobo Xiaod ; e ; Xiaorong Zhua ; zxr1967@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：COX ; cyclooxygenases ; DMEM ; Dulbecco's modified Eagle's medium ; ELISA ; enzyme-linked immunosorbent assay. ; HA ; hypodermin A. ; EP ; E-type prostanoid. ; IFN ; interferon. ; IL ; interleukin. ; PGE2 ; prostaglandin E2
- 刊名：Transplant Immunology
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：33
- 期：3
- 页码：198-203
- 全文大小：826 K
文摘
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Investigated the possibility of HA used to ameliorate acute transplantation rejection.
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Ectopic expression of HA activates PGE2 secretion.
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HA can inhibit IL-2 and IFN-γ expression but promote IL-10 expression.
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EP4 receptor involves in HA-regulated cytokine expression.
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