Neurotrophic effects of amyloid precursor protein peptide 165 in vitro
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- 作者：Jie Yao1 ; Lina Ma1 ; Rong Wang ; rong_wang72@aliyun.com" class="auth_mail" title="E-mail the corresponding author ; Shuli Sheng ; Zhijuan Ji ; Jingyan Zhang
- 关键词：Diabetic encephalopathy ; Peptide 165 ; Neurotrophy ; Pepsin digestion
- 刊名：Brain Research Bulletin
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：120
- 期：Complete
- 页码：58-62
- 全文大小：1089 K
文摘
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APP 17 has neuroprotective effects but is not optimal for an oral administration.
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P165 is the best analogue from seven analogues in terms of its neurotrophic effect.
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P165 can resist pepsin digestion and maybe is optimal for an oral administration.
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