Our in vitro results demonstrate a high biocompatibility of Cytocare® resulting in a better viability of ASCs when cultured in Cytocare® compared to culture medium (p < 0.05, Mann and Whitney). Cytocare® also permits their bioavailability and proliferation, making it a potential transfer vehicle that can retain the cells before their integration around the recipient site. Finally, our animal experiment shows that the ASC + Cytocare® combination is well tolerated.
In conclusion, Cytocare® can be used as a biocompatible scaffold for cultured ASCs in therapeutic treatments, ensuring ASC bioavailability, as well as evidence of excellent tolerance in nude mice.
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