Semaphorin and plexin gene expression is altered in the prefrontal cortex of schizophrenia patients with and without auditory hallucinations
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- 作者：Javier Gilabert-Juana ; b ; c ; Ana Rosa Sá ; ezb ; Guillermo Lopez-Camposd ; Noelia Sebastiá ; -Ortegab ; Rocio Gonzá ; lez-Martí ; nezb ; c ; Juan Costae ; Josep Marí ; a Haroa ; e ; Luis F. Calladoa ; f ; J. Javier Meanaa ; f ; g ; Juá ; n Nachera ; c ; Julio Sanjuá ; na ; h ; Marí ; a Dolores Moltó ; a ; b ; dmolto@uv.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Schizophrenia ; Auditory hallucinations ; Prefrontal cortex ; Gene expression ; Semaphorins ; Plexins
- 刊名：Psychiatry Research
- 出版年：2015
- 出版时间：30 October 2015
- 年：2015
- 卷：229
- 期：3
- 页码：850-857
- 全文大小：1060 K
文摘
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Gene expression analysis was conducted in schizophrenic postmortem brain samples.
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Axon Guidance pathway was found differentially expressed among SNA, SA and CNT.
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Some semaphorin and plexin genes are upregulated or downregulated in the patients.
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SNA showed more alterations in frontal regions than SA in neural plasticity genes.
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