Bioactive compounds from the bark of Eucalyptus exserta F. Muell.

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• 作者：Jingjing Li^a ; ^b ; Hanhong Xu^a ; ^b ; ^{hhxu@scau.edu.cn}
• 关键词：Eucalyptus exserta ; Chemical constituents ; 1 ; 3 ; 8 ; 9-Tetrahydroxydibenzo[b ; d]pyran-6-one ; Molluscicidal activity ; Cytotoxicity ; Nematicidal activity
• 刊名：Industrial Crops and Products
• 出版年：2012
• 出版时间：November, 2012
• 年：2012
• 卷：40
• 期：Complete
• 页码：302-306
• 全文大小：375 K

文摘

A new phenolic compound, 1,3,8,9-tetrahydroxydibenzo[b,d]pyran-6-one (6), was isolated from the methanol extract of the bark of Eucalyptus exserta F. Muell. by activity-guided isolation method, along with nine known compounds, ¦Â-sitosterol (1), 2,6-dimethoxy-1,4-benzoquinone (2), sideroxylin (3), 3,3?di-O-methylellagic acid (4), 1-monopalmitin (5), (?-catechin (7), yangambin (8), (24R)-24-ethyl-5¦Á-cholestane-3¦Â,5¦Á,6¦Â-triol (9) and ¦Â-sitosterol xyloside (10). Their structures were determined by spectroscopic methods. Compounds 4-6 and 8 exhibited moderate molluscicidal activity against Pomacea canaliculata (Lamarck). Compound 4 showed potent cytotoxicity against Spodoptera litura Fabricius cells. Compounds 2, 4-6 and 8 also exhibited nematicidal activity against Meloidogyne incognita (Kofoid and White). The results demonstrated that the bark of E. exserta is a promising source of valuable compounds. Some of these chemical constituents showed the potential for their molluscicidal and nematicidal applications.