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Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression
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文摘

Lin28A binds a consensus DNA sequence in vivo and in vitro

Lin28A is primarily associated with active transcription in mESCs

Lin28A recruits Tet1 to common genomic loci

Lin28A complexes with Tet1 to regulate DNA methylation and gene expression

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