Dietary methionine level influences growth and lipid metabolism via GCN2 pathway in cobia (Rachycentron canadum)
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- 作者：Zhen Wang ; Kangsen Mai ; Wei Xu ; Yanjiao Zhang ; Yinglong Liu ; Qinghui Ai ; qhai@ouc.edu.cn" class="auth_mail" title="E-mail the corresponding author ; aiqinghui@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：SREBP-1 ; sterol regulatory element binding protein-1 ; PPARγ ; peroxisome proliferator activated receptor γ ; FAS ; fatty acid synthetase ; ACC-1 ; acetyl-coenzyme A carboxylase-1 ; SCD-1 ; stearoyl-CoA desaturase-1 ; G6PD ; glucose-6-phosphate dehydrogenase ; PPARα ; peroxisome proliferator activated receptor α ; CPT-1 ; carnitine acyl transferase-1 ; HSL ; hormone sensitive lipase ; LPL ; lipase lipoprotein lipase ; GCN2 ; general control non-derepressible kinase 2 ; ATF4 ; activating transcription factor 4 ; C/EBPβ
- 刊名：Aquaculture
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：454
- 期：Complete
- 页码：148-156
- 全文大小：665 K
文摘
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Dietary methionine promotes growth of juvenile cobia.
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The hepatic lipid synthetic ability is inhibited and fatty acid oxidation ability is enhanced in the fish fed with methionine deficient diet.
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The hepatic GCN2 pathway related genes are up-regulated by dietary methionine deficiency.
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