USP12 regulates cell cycle progression by involving c-Myc, cyclin D2 and BMI-1
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- 作者：Li-Juan Tanga ; liyu322@126.com" class="auth_mail" title="E-mail the corresponding author ; Yu Lib ; 805593762@qq.com" class="auth_mail" title="E-mail the corresponding author ; Ying-Li Liua ; yingliliu2007@163.com" class="auth_mail" title="E-mail the corresponding author ; Jian-Min Wanga ; wjmwjm_0103@163.com" class="auth_mail" title="E-mail the corresponding author ; Dian-Wu Liua ; liudw56@tom.com" class="auth_mail" title="E-mail the corresponding author ; Qing-Bao Tiana ; tqb1980@hebmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：USP12 ; ubiquitin-specific protease 12 ; UPS ; ubiquitin proteasome system ; DUBs ; deubiquitinating enzymes ; CC ; cervical cancer ; SIAH1 ; seven in absentia homolog 1 ; TAK1 ; TGF-β-activated kinase 1 ; PC ; prostate cancer ; AR ; androgen receptor ; PHLPP ; PH domain leucine-rich repeat protein phosphatase ; HPV ; human papillomavirus ; UAF1 ; USP1-associated factor 1
- 刊名：Gene
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：578
- 期：1
- 页码：92-99
- 全文大小：993 K
文摘
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Inhibition of USP12 enzyme activity blocks HeLa cell cycle.
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Enhancement of USP12 catalytic activity promotes HeLa cell cycle.
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Regulation of HeLa cell cycle by USP12 may be linked with c-Myc, cyclin D2 and BMI-1.
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