Microfluidic chip-based silver nanoparticles aptasensor for colorimetric detection of thrombin
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- 作者：Yaju Zhao ; Xiaohui Liu ; Jie Li ; Weibing Qiang ; Liang Sun ; Hui Li ; Danke Xu ; xudanke@nju.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Aptamer ; Silver nanoparticles ; Colorimetric detection ; Protein ; Microfluidic chip
- 刊名：Talanta
- 出版年：2016
- 出版时间：1 April 2016
- 年：2016
- 卷：150
- 期：Complete
- 页码：81-87
- 全文大小：2383 K
文摘
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A colorimetric microfluidic chip-based silver nanoparticles aptasensor was designed.
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The detection principle was based on the color of AgNPs without signal amplification.
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This system combined microfluidic chip with colorimetric quantitative analysis.
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The detection limit of thrombin was as low as 20 pM with excellent specificity.
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