Preparation and spectroscopic characterization of novel cyclodiphosph(V)azane of N¹-2-pyrimidinylsulfanilamide complexes: Magnetic, thermal and biological activity studies

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• 作者：Carmen M. Sharaby ; Gehad G. Mohamed ; M.M. Omar
• 关键词：Sulfadiazine ; Phosphorus pentachloride ; Sulfur ; Glycine ; Transition metals ; Thermal analysis ; Biological activity
• 刊名：Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
• 出版年：2007
• 出版时间：April 2007
• 年：2007
• 卷：66
• 期：4-5
• 页码：935-948
• 全文大小：994 K

文摘

Hexachlorocyclophosph(V)azane of sulfadiazine, (sulfupyrimidine) [N¹-2-pyrimidinylsulfanilamide] (H₂L¹), was prepared and reacted with sulfur and glycine to give (H₂L²) and (H₂L³) ligands, respectively. The prepared ligands; H₂L¹, H₂L² and H₂L³, react in 1:2 [ligands]:[metal ions] molar ratio with transition metals to give coloured complexes in a relatively good yields. The complexes were characterized using different physicochemical techniques, namely elemental analyses, IR, UV–vis, mass, ¹H NMR, molar conductance, magnetic, solid reflectance and thermal analysis. The spectral data reveal that all the ligands behave as neutral bidentate ligands and coordinated to the metal ions via pyrimidine-N and enolic sulfonamide OH. The molar conductance data reveal that the complexes are non-electrolytes while UV–vis, solid reflectance and magnetic moment data have been shown that the complexes have octahedral geometry. The thermal behaviour of the complexes is studied and the thermodynamic activation parameters are calculated. The ligands and their complexes show high to moderate bactericidal activity.