Application of synthetic peptides for detection of anti-citrullinated peptide antibodies
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- 作者：Nicole Hartwig Triera ; Bettina Eide Holma ; Ole Slotb ; Henning Lochtc ; Hanne Lindegaardd ; Anders Svendsene ; Christoffer Tandrup Nielsenf ; Sø ; ren Jacobsenf ; Elke Theanderg ; Gunnar Houena ; gh@ssi.dk" class="auth_mail" title="E-mail the corresponding author
- 关键词：Citrullinated epitopes ; EBNA-1 ; Streptavidin capture ELISA ; Peptides
- 刊名：Peptides
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：76
- 期：Complete
- 页码：87-95
- 全文大小：1522 K
文摘
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Anti-citrullinated peptide antibodies to a panel of five citrullinated EBNA-1 peptides were found in 67% of RA sera.
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A single peptide, ARGGSRERARGRGRG-Cit-GEKR, was recognized by 53% of the RA sera.
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Citrullinated EBNA-1 peptides may be considered a substrate for the detection of ACPAs.
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