Comparative transcriptome analysis of Brucella melitensis in an acidic environment: Identification of the two-component response regulator involved in the acid resistance and virulence of Brucella
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- 作者：Qianhong Liua ; qianhongliu@126.com" class="auth_mail" title="E-mail the corresponding author ; Xingyu Liub ; Feng Yana ; Yuhua Hea ; Jie Weia ; Yuanyuan Zhanga ; Lu Liua ; Youpeng Suna
- 关键词：Brucella melitensis ; Two-component response regulator ; Acid stress ; Virulence
- 刊名：Microbial Pathogenesis
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：91
- 期：Complete
- 页码：92-98
- 全文大小：579 K
文摘
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A description of 113 genes in an acidic environment of Brucella through comparative transcriptome analysis.
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These genes distributed in 51 pathways, in which ribosome and photosynthesis pathways were significantly enriched.
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Six pathways tightly related to the intracellular survival and virulence of Brucella were analyzed.
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Confirmation of the two-component response regulator involved in the acid resistance and strength of Brucella.
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