Acetylation of histones in neocortex and hippocampus of rats exposed to different modes of hypobaric hypoxia: Implications for brain hypoxic injury and tolerance
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- 作者：Mikhail Samoilova ; Anna Churilovaa ; Tatjana Gluschenkoa ; Oleg Vetrovoya ; d ; Natalia Dyuzhikovac ; Elena Rybnikovab ; rybnikova1@rambler.ru" class="auth_mail" title="E-mail the corresponding author
- 关键词：SH ; severe hypoxia ; HDACs ; histone deacetylases ; HATs ; histone acetyltransferases ; DNMTs ; DNA methyltransferases ; GR ; glucocorticoid receptor ; MR ; mineralocorticoid receptor ; pan-ac ; pan-acetyl proteins ; H3K24ac ; acetylated histone H3 (Lys24)
- 刊名：Acta Histochemica
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：118
- 期：2
- 页码：80-89
- 全文大小：3479 K
文摘
- ass="listitem" id="list_lis0005">
- ass="label">•
ar0005">Histone acetylation is linked to the activation of gene expression.
- ass="label">•
ar0010">Injurious hypoxia induces deacetylation of histones in rat brain neurons.
- ass="label">•
ar0015">Protective hypoxic preconditioning stimulated acetylation of histones in the brain.
- ass="label">•
ar0020">Acetylation of histones is necessary for development of brain hypoxic tolerance.
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