What is the impact of abnormal dopamine signaling on decision making in task specific dystonia?

We studied the neural response in a reinforcement context using fMRI in 31 writer's cramp patients compared to 35 controls.

Patients showed specific increased response after negative feedback in middle ACC (BA 32)

This finding demonstrated disturbed integration of reinforcement history in a task specific dystonia.

The reward system might contribute to the pathogenesis in writer’s cramp