Relationship between urodynamic patterns and lower urinary tract symptoms in Chinese women with a non-neurogenic bladder

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• 作者：Linhui Wang¹ ; Cunzhou Wang¹ ; Chuangyu Qu ; ^{qu_cy@sohu.com" class="auth_mail" title="E-mail the corresponding author} ; Lei Yin ; ^{yin202@163.com" class="auth_mail" title="E-mail the corresponding author} ; Danfeng Xu ; Xingang Cui ; Bing Liu
• 关键词：Bladder outlet obstruction ; Detrusor underactivity ; Idiopathic detrusor overactivity ; Idiopathic sphincter overactivity ; Urodynamics
• 刊名：Asian Journal of Urology
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：3
• 期：1
• 页码：10-19
• 全文大小：2137 K

文摘

To investigate the urodynamic study (UDS) patterns, obstruction status, continence status, and their correlations among neurologically intact women with lower urinary tract symptoms (LUTS) through an epidemiological and logistic regression analyses.

Methods

We retrospectively analyzed the UDS data of 3265 neurologically intact women with LUTS (2002–2014). Five UDS patterns were identified: normo-active detrusor/sphincter (NA, or DSI, detrusor/sphincter intact), idiopathic detrusor overactivity (IDO), idiopathic sphincter overactivity (ISO), IDO + ISO, and detrusor underactivity (DUA). Analyses of UDS pattern distribution and stratification were performed (based on a modification of the European Urological Association-Madersbacher classification system), and their correlations with bladder outlet obstruction (BOO) and stress urinary incontinence (SUI) status were evaluated via logistic regression analysis.

Results

NA, IDO, IDO + ISO, ISO, and DUA were noted in 927 (28.4%), 678 (20.8%), 320 (9.8%), 689 (21.1%), and 651 (19.9%) cases, respectively. Moreover, storage, storage + voiding, and voiding symptoms were noted in 62.4%, 21.1%, and 16.5% cases, respectively, whereas BOO and SUI were observed in 12.1% and 29.0% cases, respectively. The risk factors for BOO included NA, IDO, ISO, and IDO + ISO, whereas the protective factors against BOO included storage symptoms, SUI, storage + voiding symptoms, and complaint duration within 1–12 months. NA was the only risk factor for SUI, whereas BOO, storage + voiding symptoms, IDO, and storage symptoms were protective factors for SUI.

Conclusion

Five UDS patterns were identified among neurologically intact women with LUTS. Functional abnormalities of the detrusor and/or sphincter were the main causes of LUTS, and were correlated with the BOO or SUI status. Thus, the UDS pattern can provide additional information regarding the risk factors for BOO or SUI status, as compared to symptomatic typing.