Relapsing sepsis episodes of Escherichia coli with CTX-M ESBL or derepressed ampC genes in a patient with chronic autoimmune pancreatitis complicated by IgG4 hypergammaglobulinaemia

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• 作者：T. Tuuminen¹ ; ² ; ^{tamara.tuuminen@islab.fi" class="auth_mail" title="E-mail the corresponding author} ; M. Ö ; sterblad³ ; S. Hä ; mä ; lä ; inen⁴ ; R. Sironen⁵ ; ⁶ ; ⁷
• 关键词：Autoimmune pancreatitis ; bacteraemia ; ESBL ; IgG4 hypergammaglobulinaemia ; relapsing sepsis
• 刊名：New Microbes and New Infections
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：9
• 期：Complete
• 页码：50-53
• 全文大小：327 K

文摘

Bloodstream recurrent infections have been reported for a variety of opportunistic bacteria. These are often either catheter related or are caused by indwelling devices. A case of relapsing sepsis with two Escherichia coli strains carrying extended-spectrum β-lactamase and derepressed ampC genes is reported. The patient had seven episodes of bloodstream infections within 1 year and was diagnosed with chronic autoimmune pancreatitis and IgG4 hypergammaglobulinaemia. Abscesses were found in his spleen and pancreas cauda, which was finally resected. Relapses of bacteraemia with resistant enterobacteria should be considered during perioperative protection. Surgical removal of the infective focus could be curative.