Fast fish face fewer mitochondrial mutations: Patterns of dN/dS across fish mitogenomes
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- 作者：Jeff H.T. Strohma ; jstrohm@uoguelph.ca" class="auth_mail" title="E-mail the corresponding author ; Rodger A. Gwiazdowskib ; Robert Hannera
- 关键词：OXPHOS ; oxidative phosphorylation ; Mitogenome ; mitochondrial genome ; dN/dS ; ratio of non-synonymous to synonymous mutations ; PIC ; phylogenetically independent contrasts ; PLAGL2 ; Pleiomorphic adenoma gene-like 2 ; RIPK4 ; Receptor-interacting serine-threonine kinase 4 ; ZIC1 ; Zic family member 1 ; GARD ; Genetic Algorithm Recombination Detection ; REV ; General Reversible Model ; Branch-site REL ; Branch-site random effects likelihood ; MEME ; Mixed effects model of evolution ; R ; = ; Ts/Tv ; transitio
- 刊名：Gene
- 出版年：2015
- 出版时间：1 November 2015
- 年：2015
- 卷：572
- 期：1
- 页码：27-34
- 全文大小：646 K
文摘
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High performance fish face less mitogenome substitutions compared to sedentary fish.
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This trend was not detected in housekeeping genes of the nuclear genome.
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Not true in regions of high functional importance: protein subunit binding sites
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High performance energy requirements = increased mitogenome purifying selection
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