Tocols are the most powerful chain-breaking antioxidants in plants and animals.
The food matrix plays a significant role in selection of suitable analytical method.
Supercritical fluid extraction is emerging as an eco-extraction technique for tocols.
RP-HPLC is the gold standard for analysis of tocols in food samples.
APCI and ESI in negative ion mode are most sensitive for LC–MS detection of tocols.
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