Nitrogen-rich functional groups carbon nanoparticles based fluorescent pH sensor with broad-range responding for environmental and live cells applications

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• 作者：Bingfang Shi^a ; ^b ; ¹ ; Yubin Su^a ; ¹ ; Liangliang Zhang^a ; ^{liangzhang319@163.com" class="auth_mail" title="E-mail the corresponding author} ; Rongjun Liu^a ; Mengjiao Huang^a ; Shulin Zhao^a ; ^{zhaoshulin001@163.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Fluorescent pH sensor ; Nitrogen-rich functional groups ; Carbon nanoparticles ; Live-cell image ; Environmental monitoring
• 刊名：Biosensors and Bioelectronics
• 出版年：2016
• 出版时间：15 August 2016
• 年：2016
• 卷：82
• 期：Complete
• 页码：233-239
• 全文大小：1747 K

文摘

A nitrogen-rich functional groups carbon nanoparticles (N-CNs) based fluorescent pH sensor with a broad-range responding was prepared by one-pot hydrothermal treatment of melamine and triethanolamine. The as-prepared N-CNs exhibited excellent photoluminesence properties with an absolute quantum yield (QY) of 11.0%. Furthermore, the N-CNs possessed a broad-range pH response. The linear pH response range was 3.0 to 12.0, which is much wider than that of previously reported fluorescent pH sensors. The possible mechanism for the pH-sensitive response of the N-CNs was ascribed to photoinduced electron transfer (PET). Cell toxicity experiment showed that the as-prepared N-CNs exhibited low cytotoxicity and excellent biocompatibility with the cell viabilities of more than 87%. The proposed N-CNs-based pH sensor was used for pH monitoring of environmental water samples, and pH fluorescence imaging of live T24 cells. The N-CNs is promising as a convenient and general fluorescent pH sensor for environmental monitoring and bioimaging applications.