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MMP2-sensing up-conversion nanoparticle for fluorescence biosensing in head and neck cancer cells
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文摘

We fabricated an MMP2-recognizing upconversion nanoparticle, named UCNP@p-Au.

UCNP@p-Au conjugated with MMP-recognizing polypeptides and folic acid.

We used 3.5-nm AuNPs to quench the upconversion fluorescence of UCNP.

UCNP@p-Au is endocytosed by MMP2-expressing cells, and is little cytotoxicity.

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